At the CURE Educated Patient® Breast Cancer Summit, Dr. Anastasia Martinova, a breast medical oncologist at the University of Southern California, outlined the role of integrative oncology in supporting patients with metastatic breast cancer. She emphasized evidence-based complementary therapies that can be used alongside standard treatment to manage symptoms, improve well-being and empower patients.
Integrative oncology combines conventional cancer treatments with complementary approaches such as nutrition, exercise, mind-body practices, acupuncture and massage. These therapies are intended to complement, not replace, standard care and address the whole person by targeting symptoms including fatigue, pain, nausea, insomnia, anxiety and depression, as well as emotional and spiritual needs.
Nutrition is a central component. There is no single “cancer diet,” but patients are advised to follow a balanced diet rich in vegetables, fruits, whole grains, lean proteins and healthy fats. Mediterranean-style diets that emphasize plant-based foods, olive oil and fish have the strongest evidence for promoting overall health. Extreme or unproven diets should be avoided, and patients with appetite or nutrition problems should consult a dietitian.
Herbal supplements may help manage some symptoms but carry risks and can interact with cancer treatments. Martinova recommended prioritizing diet and lifestyle, consulting a healthcare professional before starting supplements, and using trusted resources such as the Memorial Sloan Kettering About Herbs database. Examples of herbs with some supporting evidence include ginger for nausea, ginseng and reishi for fatigue, chamomile for mild depression or nausea, and lavender for anxiety and sleep.
Exercise is a key element of integrative care. Structured exercise programs have been shown to reduce fatigue, improve physical function and enhance quality of life for patients without bone metastases. Patients should begin gradually with manageable routines and increase activity over time. Mind-body practices such as meditation, yoga and tai chi can additionally support emotional well-being and reduce stress.
Acupuncture can relieve nausea, pain, fatigue and, in some cases, neuropathy, while massage therapy can ease muscle tension and boost mood and energy. Oncology-trained practitioners are recommended when available; simple tools such as acupressure wristbands can provide at-home symptom relief if professional services are inaccessible.
Palliative care should be introduced early to address symptoms and provide supportive care at any stage of cancer, not only at end of life. Early palliative care helps manage pain, fatigue and nausea, supports emotional needs and aids decision-making. Sexual health is an important but often overlooked aspect of care and should be discussed openly with the oncology team or a specialist.
Practical recommendations include communicating openly with the care team about symptoms and any supplements or medications, starting slowly with one or two therapies tailored to individual needs, and avoiding unsafe or unproven products. Trusted resources cited by Martinova include the Memorial Sloan Kettering About Herbs database, the Society for Integrative Oncology and the American Cancer Society.
“Integrative care supports the person as a whole—mind, body and spirit,” Martinova said. “It complements oncology care, improves quality of life and empowers patients to take an active role in their journey.”
Source: “Utilizing Integrative Medicine,” Dr. Anastasia Martinova. Presented at CURE Educated Patient Summit on Metastatic Breast Cancer; December 20, 2025.
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