As 2026 approaches, Oncology Central reviews its top 10 articles of 2025, spanning news, conference coverage and opinion pieces that shaped oncology practice and research over the year.
10. What to look out for at ASH 2025 — A comprehensive conference guide highlighted agenda picks and helped readers navigate the 8,200 abstracts presented at the American Society of Hematology Annual Meeting and Exposition.
9. ASCO 2025 guide — Our ASCO conference roundup summarized breaking news, key themes and social media highlights from the meeting, with additional events coverage available across the site.
8. Artificial sweetener sucralose shown to dampen immunotherapy effectiveness — Research reported that sucralose can hinder the effectiveness of anti‑PD‑1 immune checkpoint inhibitors by altering the gut microbiome; the study also found probiotic supplements counteracted these effects.
7. ASCO 2025: Inavolisib‑palbociclib‑fulvestrant improves overall survival for advanced breast cancer — Coverage of the Phase III INAVO120 trial detailed improved survival outcomes for certain patients treated with the inavolisib, palbociclib and fulvestrant combination.
6. How transformational technologies are shaping the future of cancer care — An opinion piece from AstraZeneca experts examined how computational pathology, circulating tumour DNA and multi‑omics are changing trial design and advancing precision oncology, and offered perspectives on clinical integration.
5. Could COVID‑19 mRNA vaccines help treat cancer? — Reporting from ESMO 2025 described progress toward a universal cancer vaccine, with co‑author Elias Sayour noting that the implications could revolutionize oncologic care.
4. Bridging the gaps: how strategic charity partnerships are transforming head and neck cancer care — Danni Heath of the Get A‑Head Charitable Trust outlined treatment delays and care inequalities and explained how strategic charity partnerships are delivering patient‑centred solutions.
3. Burnout: strategies and tools for clinicians — A webinar convened leading experts to address physician burnout in oncology, exploring root causes, practical clinician steps and institutional strategies; the session is available on demand.
2. World‑first trial highlights survival benefits of exercise for colon cancer — A multinational trial of 889 colon cancer patients across six countries found that structured exercise programs significantly improved survival, underscoring the real‑world impact of lifestyle interventions.
1. What do Trump’s NIH restrictions mean for cancer research? — Coverage of the administration’s indefinite suspension of research‑grant reviews examined the disruption to the scientific community and reinforced Oncology Central’s commitment to providing a free platform for oncologists to stay informed and support equitable cancer care.
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